深水铺管船的动力定位能力评估系统

为解决评估铺管船作业能力的难题,提出一种适用于评估铺管船动力定位能力的方法,开发了动力定位能力评估程序系统,并针对高海况环境条件设计了优化的辅助作业方案.采用数值计算方法对铺管船作业期间的平均二阶力、风载荷以及流载荷进行仿真计算,建立了环境载荷与动力定位系统提供的推力之间的平衡关系,给出了用于评估铺管船动力定位能力的系统模块,采用动力定位能力包络线的方式表达动力评估结果.在高海况作业中给出安全建议,即采用辅助拖轮作用于船舶适当位置以增强动力定位能力,从而降低工程作业风险.     

An Economic Model-Based Matching Approach Between Buyers and Sellers Through a Broker in an Open E-Marketplace

A broker in an open e-marketplace enables buyers and sellers to do business with each other. Although a broker plays an important role in e-marketplaces, theory and guidelines for matching between buyers and sellers in multi-attribute exchanges are limited. Therefore, a challenge for a broker’s responsibility is how to maximize a buyer’s total satisfaction degree as its goals under the consideration of trade-off between a buyer’s buying quantity and price paid to a seller, and other attributes. To solve this challenge, this paper proposes an economic model-based matching approach between a buyer’s requirements and a seller’s offers. The major contributions of this paper are that (i) a broker can model a seller’s price policy as per a buyer’s buying quantity through communication between a broker and a seller; (ii) due to each buyer’s different quantity demand, a broker models a buyer’s satisfaction degree as per a buyer’s buying quantity based on communication between a broker and a buyer; and (iii) to carry out a broker’s matching processes, an objective function and a set of constraints are generated to help a broker to maximize a buyer’s total satisfaction degree. Experimental results demonstrate the good performance of the proposed approach.     

考虑凸形障碍的应急设施选址与资源分配决策研究

应急设施是应急救援的依托载体,其科学合理的选址事关应急救援的紧迫性和应急资源分配的及时性,障碍约束下的应急设施选址与应急资源分配决策研究具有重要的战略意义.从需求区域的视角和应急设施应急服务质量的视角构建基于障碍约束、容量及安全库存约束的应急设施选址与资源分配优化模型,引入安全库存机制,综合考虑时间性、经济性及地理阻断等多重约束限制,剖析选址和应急物资分配的决策过程,进行应急设施的选址决策和应急物资分配预案的制定.设计灰狼优化算法(GWO)与可视凸点绕障路径耦合算法求解模型,结果表明:所设计算法能有效实现绕障路径的优化,且在需求区域的不同时间满意度偏好下,获得最优的选址-分配方案,研究成果将为应急设施选址与资源分配提供模型和方法设计.     

普通话在线游戏学习系统的研究与应用

针对希望进一步掌握普通话口语学习的外国学习者,该研究提出了一种普通话游戏学习系统.系统的学习模式结合了计算机技术和语言学研究成果,打破了传统的教学模式的限制,对学习者进行实时评测,提供学习报告与口语学习的最终评定结果.结果表明,该系统能够较为有效地辅助外国学习者的普通话口语学习.     

APCI5000电气自动化成套装置设计

电气自动化成套装置种类繁多，并广泛应用于电力系统．结合现场实际商业运行期所积累的经验，并根据市场预测以及目前工控机发展动态，提出了采用APCI5000工业控制计算机实现电气自动化成套装置设计的最佳方案．     

LaMnO3不同晶位掺杂的磁电阻效应

基于研究钙钛矿型氧化物磁电阻效应的目的,采用固相反应法制备了实验所需的单相多晶样品,主要就La位二价金属离子掺杂和稀土互掺及Mn位掺杂对LaMnO3磁电阻影响的实验结果作比较研究,发现La位稀土互掺对磁电阻的影响可以用晶格效应来解释,并明确指出La位和Mn位掺杂是提高和调制钙钛矿型锰氧化物超大磁电阻效应的一种有效途径.     

浅谈智能模糊控制恒压供水系统

文章介绍在变频恒压供水系统的基础上采用智能模糊控制等特性来完成恒压供水。     

波纹纤维混凝土的动力耗散研究

根据曲线纤维的几何特点和受力性能 ,推导了波纹纤维混凝土的本构关系 ,在本构理论的基础上进行动力耗散研究     

噬菌体展示禽流感病毒抗原变异性基因片段文库的构建

构建T7噬菌体展示禽流感病毒抗原变异性基因片段文库. 首先， 从Gene Bank中查找筛选禽流感病毒抗原变异性基因, 将其截短、 修饰、 简并后得到禽流感病毒抗原变异性基因微阵列. 其次， 将合成的禽流感病毒抗原变异性基因片段文库扩增、 酶切, 链接到双酶切后的T7噬菌体载体基因上, 构成重组噬菌体DNA. 最后， 重组噬菌体DNA经体外包装和扩增, 得到T7噬菌体展示文库, 并进行T7噬菌体展示文库滴度、 重组率和免疫活性测定. 实验结果表明, 从Gene Bank中查找、 筛选、 剪切和修饰共获得96 258条序列构建T7噬菌体展示文库, 原始文库滴度为3.6×107个菌落/mL, 重组率大于90%. 用禽流感病毒H5N1抗体进行捕获, 经聚合酶链式反应(PCR)鉴定, 得到理想目的条带, 证明噬菌体表面展示蛋白具有抗原活性, 可用于禽流感病毒感染患者的快速检测及抗原表位筛选.     

The Shwachman-Bodian-Diamond syndrome protein mediates translational activation of ribosomes in yeast

The autosomal recessive disorder Shwachman-Diamond syndrome, characterized by bone marrow failure and leukemia predisposition, is caused by deficiency of the highly conserved Shwachman-Bodian-Diamond syndrome (SBDS) protein. Here, we identify the function of the yeast SBDS ortholog Sdo1, showing that it is critical for the release and recycling of the nucleolar shuttling factor Tif6 from pre-60S ribosomes, a key step in 60S maturation and translational activation of ribosomes. Using genome-wide synthetic genetic array mapping, we identified multiple TIF6 gain-of-function alleles that suppressed the pre-60S nuclear export defects and cytoplasmic mislocalization of Tif6 observed in sdo1Delta cells. Sdo1 appears to function within a pathway containing elongation factor-like 1, and together they control translational activation of ribosomes. Thus, our data link defective late 60S ribosomal subunit maturation to an inherited bone marrow failure syndrome associated with leukemia predisposition.